Genomics-informed drug-repurposing strategy identifies two therapeutic targets for preventing liver disease associated with metabolic dysfunction.
Hannah M Seagle, Alexis T Akerele, Joseph A DeCorte, Jacklyn N Hellwege, Joseph H Breeyear, Jeewoo Kim, Michael G Levin, Samuel Khodursky, Adam Bress, Kyung Min Lee, Jens Meiler, Dipender Gill, Jennifer S Lee, Kent Heberer, Donald R Miller, Peter D Reaven, Kyong-Mi Chang, Julie A Lynch, Nikhil K Khankari, Megan M Shuey, Todd L Edwards, Marijana Vujkovic
Adherence to ready-to-use therapeutic food in older children with sickle cell anaemia and severe acute malnutrition: a mixed-methods study in a low-income setting.
Amanda Brechko, Shehu U Abdullahi, Safiya Gambo, Hassan Adam Murtala, Halima Kabir, Khadija A Shamsu, Virginia A Stallings, Mark Rodeghier, Ahalya Ramesh, Ashley Sellers, David G Schlundt, Michael R DeBaun, Lauren J Klein
Foix-Alajouanine syndrome: A systematic review and meta-analysis of presentation, management, and outcomes.
Sean O’Leary, Nathan Fredricks, Peace Odiase, Sonia Pulido, Usama AlDallal, Ariadna Robledo, Christopher Thang, Umaru Barrie, Salah Aoun
Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease.
Huang Kuang, Bei-Ning Wang, Xiao- Yu Jia, Zhao Cui, Xiao-Juan Yu, Nan Jiang, Dorin-Bogdan Borza, Ming-Hui Zhao
Priapism Before and After Hematopoietic Stem Cell Therapy in Individuals with Sickle Cell Disease.
Jose A Mejias, Santosh L Saraf, Clifford M Takemoto, Mark Rodeghier, Michael R DeBaun
Hydroxypropyl-Beta-Cyclodextrin (HP-BCD) inhibits SARS-CoV-2 replication by modulating intracellular lipid dynamics and preventing viral replication complex formation.
Bruno Braz Bezerra, Keylla Vitória Gomes Macedo, Isadora Alonso Correa, Sharton Vinicius Antunes Coelho, Marcos Romario Matos de Souza, Barbara Martins Cordeiro, Carlos Frederico Leite Fontes, Fabiana Avila Carneiro, Flavio Matassoli, Luciana Jesus Costa, James E K Hildreth, Luciana Barros Arruda
Haplo-stem cell transplant post liver transplantation to cure sickle cell disease with related liver dysfunction: a case series.
Ali D Alahmari, Saad Alghamdi, Reem Alasbali, Sara Hisham Samarkandi, Saleh Algahtani, Hadeel Samarkandi, Syed Osman Ahmed, Dieter Broering, Hazzaa Alzahrani, Adetola Kassim, Mahmoud Aljurf, Fahad Almohareb, Waleed Al-Hamoudi
Improving automated deep phenotyping through large language models using retrieval-augmented generation.
Brandon T Garcia, Lauren Westerfield, Priya Yelemali, Nikhita Gogate, E Andres Rivera-Munoz, Haowei Du, Moez Dawood, Angad Jolly, James R Lupski, Jennifer E Posey
KDIGO-Defined Kidney Dysfunction Predicts Long-Term Outcomes in a Multi-Center Cohort of Adults with Sickle Cell Disease.
Xu Zhang, Michael R DeBaun, Kristin Wuichet, Rima Zahr, Zalaya K Ivy, Mitchell J Weiss, Alexander G Bick, Victor R Gordeuk, Santosh L Saraf
Exploring Co-production as an Implementation Strategy for Trauma-Informed Care in a Youth-Focused HIV Clinic in Memphis, Tennessee: Mixed Methods Research.
Leslie Lauren Brown, Megan L Wilkins, Robert Kenneth Douglas McLean, Jamie Lynn Stewart, Nehali D Patel, Almariana Jessica Acuña, Carolyn Marie Audet, Jessica M Sales, April C Pettit, Latrice C Pichon