Programs / Clinical & Translational Science Award

Clinical & Translational Science Award

Since 2007, Meharry has been partner with the Vanderbilt Institute for Clinical and Translational Research (VICTR), Vanderbilt’s virtual home for clinical and translational research. Supported by the Vanderbilt University Medical Center’s Office of Research and the NIH sponsored Clinical and Translational Science Award (CTSA), the mission of the institute is to transform the way ideas and research discoveries make their way from origin to patient care. VICTR provides tools and support to improve the quality of research, publications, grant writing, and training for future doctors and researchers.

Helpful Links

For more information about VICTR, visit their website below.

VICTR Team

Duane Smoot, MD, FACP, FACG, AGAF

Meharry Sub-Contract PI
School of Medicine

(615) 327-6914
dsmoot@mmc.edu

Clinical & Translational Science Award Administration Team

Clinical & Translational Science Award Research Team

Duane Smoot, MD, FACP, FACG, AGAF

Meharry Sub-Contract PI
School of Medicine

(615) 327-6914
dsmoot@mmc.edu

Clinical & Translational Science Award Publications

MiRNA-20b/SUFU/Wnt axis accelerates gastric cancer cell proliferation, migration and EMT.
Yin Peng, Ying Qin, Xiaojing Zhang, Shiqi Deng, Yuan Yuan, Xianling Feng, Wangchun Chen, Fan Hu, Yuli Gao, Jieqiong He, Yulan Cheng, Yanjie Wei, Xinmin Fan, Hassan Ashktorab, Duane Smoot, Song Li, Stephen J Meltzer, Shutong Zhuang, Na Tang, Zhe Jin

Dual activation of Hedgehog and Wnt/β-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer.
Yin Peng, Xiaojing Zhang, Huijuan Lin, Shiqi Deng, Ying Qin, Jieqiong He, Fan Hu, Xiaohui Zhu, Xianling Feng, Jian Wang, Yanjie Wei, Xinmin Fan, Huan Lin, Hassan Ashktorab, Duane Smoot, Yansi Lv, Song Li, Stephen J Meltzer, Zhe Jin

Tumor-specific overexpression of histone gene, H3C14 in gastric cancer is mediated through EGFR-FOXC1 axis.
Mudasir Rashid, Sanket Girish Shah, Tripti Verma, Nazia Chaudhary, Sukanya Rauniyar, Vidisha Bhavesh Patel, Poonam B Gera, Duane Smoot, Hassan Ashaktorab, Sorab N Dalal, Sanjay Gupta

Linking bacterial enterotoxins and alpha defensin 5 expansion in the Crohn's colitis: A new insight into the etiopathogenetic and differentiation triggers driving colonic inflammatory bowel disease.
Tanu Rana, Olga Y Korolkova, Girish Rachakonda, Amanda D Williams, Alexander T Hawkins, Samuel D James, Amos M Sakwe, Nian Hui, Li Wang, Chang Yu, Jeffrey S Goodwin, Michael G Izban, Regina S Offodile, Mary K Washington, Billy R Ballard, Duane T Smoot, Xuan-Zheng Shi, Digna S Forbes, Anil Shanker, Amosy E M'Koma

Helicobacter pylori-induced gastric cancer is orchestrated by MRCKβ-mediated Siah2 phosphorylation.
Pragyesh Dixit, Shrikant B Kokate, Indrajit Poirah, Debashish Chakraborty, Duane T Smoot, Hassan Ashktorab, Niranjan Rout, Shivaram P Singh, Asima Bhattacharyya

Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells.
Xiaojing Zhang, Yin Peng, Yuan Yuan, Yuli Gao, Fan Hu, Jian Wang, Xiaohui Zhu, Xianling Feng, Yulan Cheng, Yanjie Wei, Xinmin Fan, Yaohong Xie, Yansi Lv, Hassan Ashktorab, Duane Smoot, Song Li, Stephen J Meltzer, Gangqiang Hou, Zhe Jin