Faculty Biography

Byeongwoon Song, PhD

Associate Professor
Microbiology, Immunology, Physiology
School of Medicine
(615) 327-6698 | bsong@mmc.edu

Center Affiliations

Center for AIDS Health Disparities Research

Research Themes

Infectious Diseases, Neurodegenerative Diseases

Active Research Projects

1) Targeting lysosomal homeostasis as a therapeutic approach for Niemann-Pick disease type C 2) Role of lysosomal function in viral replication

Publications

2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.
Ashutosh Singhal, Evan S Krystofiak, W Gray Jerome, Byeongwoon Song

Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
Ashutosh Singhal, Lajos Szente, James E K Hildreth, Byeongwoon Song

Cyclodextrins: Assessing the Impact of Cavity Size, Occupancy, and Substitutions on Cytotoxicity and Cholesterol Homeostasis.
Lajos Szente, Ashutosh Singhal, Andras Domokos, Byeongwoon Song

Hyaluronic Acid-Based Biocompatible Supramolecular Assembly for Sustained Release of Antiretroviral Drug.
Byeongwoon Song, István Puskás, Lajos Szente, James E K Hildreth

Keywords

Virus; Antiviral; Lysosomal Function; Lysosomal Storage Disease; Niemann-Pick Disease Type C

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