Faculty Biography

Effects of acute and sub-chronic L-dopa therapy on striatal L-dopa methylation and dopamine oxidation in an MPTP mouse model of Parkinsons disease.
Marquitta L Smith, Jennifer King, Lemuel Dent, Veronica Mackey, Gladson Muthian, Brenya Griffin, Clivel G Charlton

Methylation reactions at dopaminergic nerve endings, serving as biological off-switches in managing dopaminergic functions.

Prenatal exposure to methanol as a dopamine system sensitization model in C57BL/6J mice.
Veronica R Mackey, Gladson Muthian, Marquitta Smith, Jennifer King, Clivel G Charlton

L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease.
Jennifer M King, Gladson Muthian, Veronica Mackey, Marquitta Smith, Clivel Charlton

Excessive S-adenosyl-L-methionine-dependent methylation increases levels of methanol, formaldehyde and formic acid in rat brain striatal homogenates: possible role in S-adenosyl-L-methionine-induced Parkinson's disease-like disorders.
Eun-Sook Lee, Hongtao Chen, Chadwick Hardman, Anthony Simm, Clivel Charlton

The role of 3-O-methyldopa in the side effects of L-dopa.
Eun-Sook Y Lee, Hongtao Chen, Jennifer King, Clivel Charlton