Faculty Biography

Chandravanu Dash, PhD, MSc

Executive Director Center for AIDS Health Disparities Research, Professor and Interim Chair, Department of Microbiology, Immunology and Physiology
Biochemistry, Cancer Biology, Neuroscience, Pharmacology
School of Medicine
(615) 327-6996 | cdash@mmc.edu

Center Affiliations

Center for AIDS Health Disparities Research, Center for Molecular & Behavioral Neuroscience

Research Themes

Infectious Diseases, Neurodegenerative Diseases, Substance Abuse

Active Research Projects

1. Role of viral capsid in HIV-1 integration. (NIH R01AI136740, Role: Principal Investigator)

2. Role of Cellular miRNAs in HIV-1 Replication. (NIH U54 MD007586, Role: Project Director)

3. Effect of HIV and cocaine on semen exosome function. (NIH R01DA042348, Role: Consortium PI)

4. Methamphetamine Research at Meharry Medical College. (NIH R24DA021471, Role: Project Director).

5. Tennessee Center for AIDS Research (TN-CFAR). (NIH P30 AI110527, Role: Key Personnel)

Publications

Bortezomib Sustains T Cell Function by Inducing miR-155-Mediated Downregulation of SOCS1 and SHIP1.
Ariana N Renrick, Menaka C Thounaojam, Maria Teresa P de Aquino, Evan Chaudhuri, Jui Pandhare, Chandravanu Dash, Anil Shanker

Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure.
Bobby Jones, Muthukumar Balasubramaniam, Joseph J Lebowitz, Anne Taylor, Fernando Villalta, Habibeh Khoshbouei, Carrie Grueter, Brad Grueter, Chandravanu Dash, Jui Pandhare

Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells.
Sabyasachi Dash, Muthukumar Balasubramaniam, Freddyson J Martínez-Rivera, Arthur Godino, Emily G Peck, Srinivas Patnaik, Mrutyunjay Suar, Erin S Calipari, Eric J Nestler, Fernando Villalta, Chandravanu Dash, Jui Pandhare

The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b.
Evan Chaudhuri, Sabyasachi Dash, Muthukumar Balasubramaniam, Adrian Padron, Joseph Holland, Gregory A Sowd, Fernando Villalta, Alan N Engelman, Jui Pandhare, Chandravanu Dash

Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Hussein Kaddour, Yuan Lyu, Jennifer L Welch, Victor Paromov, Sammed N Mandape, Shruti S Sakhare, Jui Pandhare, Jack T Stapleton, Siddharth Pratap, Chandravanu Dash, Chioma M Okeoma

Immune Control of HIV.
Muthukumar Balasubramaniam, Jui Pandhare, Chandravanu Dash

Keywords

HIV, AIDS, Virus, Retrovirus, Infection

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