Faculty Biography

Sanika Chirwa, PhD

Professor
Biochemistry, Cancer Biology, Neuroscience, Pharmacology
School of Medicine
(615) 327-6934 | schirwa@mmc.edu

Center Affiliations

Center for Molecular & Behavioral Neuroscience

Research Themes

Autoimmune Diseases, Neurodegenerative Diseases, Precision Medicine, Substance Abuse, Systems Medicine

Active Research Projects

5U54MD007593-10S1 (Adunyah S, PD; Chirwa S, PI), NIMHD/NIH. 2018 – 2021. “Sleep loss and risk for Alzheimer’s disease in African-Americans.”

U92HA31460 (Matthews-Juarez, PD; Chirwa S, Prog. Manager). HRSA/PEPFAR. 10/2019 – 9/2023. “Improving Pediatric HIV Clinical Health Outcomes and Clinical Transformation through Continuous Quality Improvement Processes – Chilenje, Matero, Kanyama, & Chawama Level-1 Hospitals. Lusaka, Zambia.”

Publications

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.
Desta Z, Gammal RS, Gong L, Whirl-Carrillo M, Gaur AH, Sukasem C, Hockings J, Myers A, Swart M, Tyndale RF, Masimirembwa C, Iwuchukwu OF, Chirwa S, Lennox J, Gaedigk A, Klein TE, Haas DW

Poor Sleep Quality Is Associated with Higher Hemoglobin A1c in Pregnant Women: A Pilot Observational Study.
Chirwa S, Nwabuisi CR, Ladson GM, Korley L, Whitty JE, Atkinson R, Clark JT

Race/ethnicity difference in the pharmacogenetics of bilirubin-related atazanavir discontinuation.
Leger P, Chirwa S, Nwogu JN, Turner M, Richardson DM, Baker P, Leonard M, Erdem H, Olson L, Haas DW

Pharmacogenetics of efavirenz discontinuation for reported central nervous system symptoms appears to differ by race.
Leger P, Chirwa S, Turner M, Richardson DM, Baker P, Leonard M, Erdem H, Olson L, Haas DW


Keywords

Sleep, Learning and Memory, Mild Cognitive Impairment, Alzheimer's Disease, Pediatric HIV.

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