Faculty Biography

Zhenbang Chen, PhD

Associate Professor
Biochemistry, Cancer Biology, Neuroscience, Pharmacology
School of Medicine
(615) 327-5775 | zchen@mmc.edu | Biosketch

Center Affiliations

Health Disparities Research Center of Excellence

Research Themes

Cancer Biology

Active Research Projects

Mechanism and oncogenic role of lysine demethylase KDM5B in prostate cancer NIH/NIMHD

Sponsored Institutional Research Program affiliation

RCMI Program in Health Disparities at Meharry Medical College

Publications

Th17 cells promote tumor growth in an immunocompetent orthotopic mouse model of prostate cancer.
Zhenling Duan, Haiyan D Miller, Xiaowei Fu, Dongxia Ge, Ben Jin, Ahmed A Moustafa, Ruoxin Lan, Kun Zhang, Zhenbang Chen, Zongbing You

Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer.
Yingqiu Xie, Haiyan Fan, Wenfu Lu, Qing Yang, Ayan Nurkesh, Tleubek Yeleussizov, Aisulu Maipas, Jiang Lu, Limara Manarbek, Zhenbang Chen, Enrico Benassi

Systematic analysis of NLMP suggests nuclear localization of RTK/MET kinases resemble cancer cell clearance.
Yingqiu Xie, Ayan A Nurkesh, Nazgul Ibragimova, Zhuldyz Zhanzak, Aizhan Meyerbekova, Zhanna Alexeyeva, Aiya Yesbolatova, Madina Satayeva, Aidana Mustafa, Limara Manarbek, Aisulu Maipas, Akerke Altaikyzy, Zhibek Keneskhanova, Burkitkan Akbay, Zhenbang Chen

Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer.
David Cunningham, Qiuyang Zhang, Sen Liu, Keshab R Parajuli, Qiang Nie, Lin Ma, Allen Zhang, Zhenbang Chen, Zongbing You

Translocator Protein PET Imaging in a Preclinical Prostate Cancer Model.
Mohammed N Tantawy, H Charles Manning, Todd E Peterson, Daniel C Colvin, John C Gore, Wenfu Lu, Zhenbang Chen, C Chad Quarles

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Irene Santos-Barriopedro, Laia Bosch-Presegué, Anna Marazuela-Duque, Carolina de la Torre, Carlota Colomer, Berta N Vazquez, Thomas Fuhrmann, Bárbara Martínez-Pastor, Wenfu Lu, Thomas Braun, Eva Bober, Thomas Jenuwein, Lourdes Serrano, Manel Esteller, Zhenbang Chen, Silvia Barceló-Batllori, Raúl Mostoslavsky, Lluis Espinosa, Alejandro Vaquero


Keywords

PTEN/AKT signaling pathway, prostate cancer, genetics and epigenetic, mouse models

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