Faculty Biography

Zhenbang Chen, PhD

Associate Professor
Biochemistry, Cancer Biology, Neuroscience, Pharmacology
School of Medicine
(615) 327-5775 | zchen@mmc.edu | Biosketch

Center Affiliations

Health Disparities Research Center of Excellence

Research Themes

Cancer Biology

Active Research Projects

Mechanism and oncogenic role of lysine demethylase KDM5B in prostate cancer NIH/NIMHD

Sponsored Institutional Research Program affiliation

RCMI Program in Health Disparities at Meharry Medical College


Th17 cells promote tumor growth in an immunocompetent orthotopic mouse model of prostate cancer.
Duan Z, Miller HD, Fu X, Ge D, Jin B, Moustafa AA, Lan R, Zhang K, Chen Z, You Z

Nuclear MET requires ARF and is inhibited by carbon nanodots through binding to phospho-tyrosine in prostate cancer.
Xie Y, Fan H, Lu W, Yang Q, Nurkesh A, Yeleussizov T, Maipas A, Lu J, Manarbek L, Chen Z, Benassi E

Systematic analysis of NLMP suggests nuclear localization of RTK/MET kinases resemble cancer cell clearance.
Xie Y, Nurkesh AA, Ibragimova N, Zhanzak Z, Meyerbekova A, Alexeyeva Z, Yesbolatova A, Satayeva M, Mustafa A, Manarbek L, Maipas A, Altaikyzy A, Keneskhanova Z, Akbay B, Chen Z

Interleukin-17 promotes metastasis in an immunocompetent orthotopic mouse model of prostate cancer.
Cunningham D, Zhang Q, Liu S, Parajuli KR, Nie Q, Ma L, Zhang A, Chen Z, You Z

Translocator Protein PET Imaging in a Preclinical Prostate Cancer Model.
Tantawy MN, Charles Manning H, Peterson TE, Colvin DC, Gore JC, Lu W, Chen Z, Chad Quarles C

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Santos-Barriopedro I, Bosch-Presegué L, Marazuela-Duque A, de la Torre C, Colomer C, Vazquez BN, Fuhrmann T, Martínez-Pastor B, Lu W, Braun T, Bober E, Jenuwein T, Serrano L, Esteller M, Chen Z, Barceló-Batllori S, Mostoslavsky R, Espinosa L, Vaquero A


PTEN/AKT signaling pathway, prostate cancer, genetics and epigenetic, mouse models